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https://doi.org/10.1246/bcsj.63.1758
Copy DOIPublication Date: Jun 1, 1990 | |
Citations: 9 |
Abstract In the series of synthetic study on peptide antibiotic nisin, a bicyclic sulfide part ring D–E in this molecule was successfully synthesized. Conjunctive sulfide rings were constructed either by one step or stepwise desulfurization reaction from corresponding disulfides by use of hexaethylphosphorus triamide. Thus, all of the ring moieties in nisin were prepared for total synthesis of this antibiotic.
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