Abstract

AbstractTwo different strategies have been considered to achieve the first total synthesis of nhatrangins A and B. The first approach based on a cross metathesis (CM) reaction was unsuccessful. The second, which combined a highly stereoselective alkylation, a diastereoselective aldolization, and finally an esterification, furnished an advanced aldehyde intermediate bearing the three contiguous stereogenic centres and the expected side‐chain.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call