Abstract

The erythrina alkaloid, 1,3,4,6-tetrahydro-3,15,16-trimethoxyerythrinan-2-ol (2- epi-erythrinitol), has been synthesized by a sequence featuring a [1+4] vinyl isocyanate-isocyanide cycloaddition followed by an intramolecular Heck reaction for assembly of the erythrinan ring system.

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