Abstract
A series of Schiff base ligands as benzylidene benzohydrazide and their hydrazone analogues (Ia-Ic) have been synthesized and then complexed with organotin(IV) moiety having general formula [R'3SnL] to get the target compounds(1–9), where L = C4H3OCONHNCHR, R = C6H5O(Ia), C4H5O(Ib), C6H3Cl2(Ic) and R' = –CH3(1–3), –CH2Ph(4–6), –Ph(7–9). They were fully characterized using FT-IR, NMR(1H, 13C and 119Sn) spectroscopy, along with elemental analysis and melting point. One of the precursor (Ib) has been analyzed by single crystal XRD to further authenticate the structure. The 119Sn NMR data suggest the molecular geometry of organotin derivatives as distorted pentagonal bipyramidal. They were also evaluated for their antibacterial, antifungal, α-amylase inhibition, DPPH, total reducing power and total antioxidant activities. Triaryltin(IV) derivatives show good antibacterial and antifungal activity. Whereas the data for antidiabetic activity demonstrated that the compounds may serve as moderately effective alpha amylase inhibitor.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
