Synthetic, spectral, thermal and antimicrobial activity studies of some transition metal complexes derived from 2-hydroxy-methylbenzaldehyde N-(4'-phenyl-1' ,3' -thiazol-2' -yl)semicarbazone

Abstract

The CO II , II , Cu II , Zn II , and II complexes of Schiff base 2-hydroxy-5-methylbenzaldehyde N-(4'-phenyl-1',3'-thiazol-2'-yl)semicarbazone have been synthesized and characterized by elemental analyses, conductivity measurements, magnetic susceptibility, UV-Visible, IR, NMR, ESR, TGA and Mass spectral data. The Schiff base behaves as tridentate ONO donor ligand and forms the complexes of the type ML stoichiometry for Zn II , Cd II and II complexes and ML 2 (metal-ligand) stoichiometry for Co, Ni and Cu, complexes and are non-electrolytic in nature. It is found that Zn, Cd II and Hg complexes exhibited tetrahedral geometry whereas Co, Ni, Cu, complexes exhibited octahedral geometry. The ligand and its complexes were tested for their antibacterial activity against Escherichia coli and Staphyloccocus aureus and antifungal activity against Aspergillus niger and Candida albicans.