Synthetic nanosrystalline materials оf thepoli-variant composition based on the system СаО–P2О5–CаF2–Н2О for correction of structural disturbances of sceleton

Abstract

The prospects for the use of synthetic nanocrystalline materials of a multivariate composition based on the system СаО–P2О5–CаF2–Н2О and additives for correcting structural defects of the skeleton are considered. It is shown that for the synthesis of nanocrystalline powders and composites of biomedical use, materials whose compositions are described by the system СаО–P2О5–CаF2–Н2О are promising. The systems of CаО–P2О5–CаF2, СаО–P2О5–Н2О were studied. A study of the CaO-P2O5-CaF2 system in the Ca3 (PO4) 2 -CaF2 section was carried out: the position of the binary eutectics and the melting points in them was determined. The experimental verification of the calculated data on the preparations of the calculated compositions by the high-temperature microscopy method is performed. On the basis of the investigations carried out, the regions of primary crystallization of phases in the four-component systems Ca3 (PO4)2-CaCO3-CaF2-Ca (OH) 2 and Ca3(PO4)2-H2O-CaF2-Ca (OH) 2, promising for use as bioceramic compositions. Based on the studies carried out in the CaO-P2O5-CaF2-H2O system, areas promising for the synthesis of materials have been identified that can be used for their technical and biological properties: 1) to correct bone tissue defects; 2) as inorganic fillers of hybrid organo-inorganic composite materials intended for the restoration of articular cartilage; 3) for gluing bone fragments and filling cavities of pathological origin; 4) to replenish the mineral composition of bones and tooth enamel.