Synthetic microbiology: from analogy to methodology.

Víctor de Lorenzo

doi:10.1111/1751-7915.12786

Abstract

Synthetic microbiology: from analogy to methodology.

Highlights

From the onset of genetic engineering in the mid-70 of the last century, microbiologists have entertained programming environmental bacteria for the sake of industrial and global sustainability
The success stories of such a trialand-error Biotechnology have been many, the time has come for a major change in the way we try to modify – and build from first principles – biological systems, in particular microorganisms
While the essence of Molecular Biology relies on the so-called central dogma (DNA ? RNA ? Proteins), Synthetic Biology (SynBio) leaves aside the evolutionary origin of biological systems and addresses instead the compositional and relational logic that makes biological systems work the way they do

Summary

Introduction

From the onset of genetic engineering in the mid-70 of the last century, microbiologists have entertained programming environmental bacteria for the sake of industrial and global sustainability. The success stories of such a trialand-error Biotechnology have been many, the time has come for a major change in the way we try to modify – and build from first principles – biological systems, in particular microorganisms.

Results

Conclusion