Abstract

AbstractAn organometallic salt composed of a new cationic p‐cymene ruthenium chloro complex containing a chelating benzaldehyde semicarbazone ligand and of the known anionic p‐cymene ruthenium trichloro complex, [(η6‐p‐cymene)Ru(bzsc)Cl]+[(η6‐p‐cymene)RuCl3]– (1) (bzsc = benzaldehyde semicarbazone) was synthesized and further characterized by IR, 1H NMR, and UV/Vis spectroscopy HR‐ESI mass spectrometry, and elemental analysis. The single‐crystal structure of 1 was also determined. The in vitro anticancer activities of the complex was evaluated against three human cancer cell lines (SGC‐7901, BEL‐7404 and CNE‐1), and the IC50 values were 20.7, 71.1 and 42.6 μM, respectively.

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