Abstract
The synthesis and structure of a zinc(II) bromide complex with caffeine (caf), [Zn(caf)(H2O)Br2], are described in comparison with [Zn(caf)(H2O)X2] (X = Cl, I) complexes. Data on the cytotoxicity of [Zn(caf)(H2O)X2] (X = Cl, Br, I) towards human tumor cell lines are presented. The bromo complex has some advantages over chloro and iodo complexes for cytotoxicity on MCF-7 breast cancer cell line, and it is comparable to the chloro complex in cytotoxicity for Jurkat human T cell leukemia.
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