Synthesis, spectroscopic characterization and antibacterial studies of some derivatives of chlorodimethylsulphoxide/tetramethylenesulphoxide ruthenium(II) and ruthenium(III) with 4-aminoantipyrine

Abstract

We report the synthesis of five complexes of three different formulations viz. [cis-RuCl2(4-antp)2], [trans-RuCl2(4-antp)2] and [X]+[trans-RuCl4(4-antp)2]− (X+ = [(DMSO)2H]+, Na+, or [(TMSO)H]+ and 4-antp = 4-aminoantipyrine) from different routes. These complexes were characterized on the basis of elemental analyses, molar conductance measurements, magnetic susceptibility, electronic spectra, FTIR, 1H-NMR and 13C{1H}-NMR spectroscopy. Complexes were screened for antibacterial activity and found to be potent against gram negative bacteria Escherichia coli. ¶This paper is dedicated to my teacher, Dr. H. Singh, Ex. Professor, D.D.U. University, Gorakhpur, UP, India.