Synthesis, spectral, structural and antibacterial studies of ONO donor aroylhydrazone and its Mo(VI) complex

Abstract

A tridentate ONO donor aroylhydrazone, 3′,5′-dichloro-2′-hydroxyacetophenone-3-methoxybenzoylhydrazone monohydrate (H2CAB·H2O) and its cis-MoO2 complex [MoO2(CAB)(DMF)]2 (DMF) (1) have been synthesized and characterized by elemental analysis, LCMS, FT-IR, UV–Vis and 1H NMR. The molecular structures were confirmed by single crystal X-ray diffraction studies. H2CAB·H2O and 1 got crystallized in a triclinic space group P1¯ as monohydrated and DMF solvated respectively. The asymmetric unit of complex 1 contains two complex molecules. All the synthesized compounds are subjected to in vitro antibacterial studies against a series of selected bacterial strains, by agar well diffusion method, using ampicillin as standard. Both the compounds are more active against Escherichia coli.