Abstract

New ferrocene derivatives – 1 H -1-phenylpyrazole-4-carboxaldehydes containing o -, m - and p -ferrocenylphenyl group at position 3 – were synthesized and characterized. The electrochemical investigation showed that the position of the ferrocenyl group does not affect the redox potential of these compounds. The X-ray crystal structure of the ortho -derivative is also presented. The screening for the in vitro antimicrobial activity against eleven bacterial and three fungal/yeast strains exhibited complete inactivity of these aldehydes, but n -butyl imines of ortho and meta derivatives showed moderate activity compared to those of the used standards.

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