Abstract
Nickel, zinc and cadmium complexes of a Schiff base derived from 4-nitro-o-phenylenediamine and 5-methoxysalicylaldehyde were synthesized and characterized using infrared, ultra violet, molar conductance measurements and nuclear magnetic resonance spectroscopy. Tetradentate schiff base complexes are widely used for the industrial purpose and also exhibit the wide range of biological activities. Hence the antibacterial activity of the Schiff base ligand and the metal complexes against some clinically important bacteria namely Escherichia coli, Proteus mirabilis, Streptococcus pneumoniae, Bacillus subtilis were investigated and the obtained results have shown that the complexes were possesses more antibacterial activity than the parent Schiff base ligand and hence could be potentially used in the preparation of anti bacterial agents.
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