Synthesis, spectral and biological studies of cobalt(II) and copper(II) complexes with Schiff base ligands

Abstract

Four new Co (II) and Cu (II) metal complexes were synthesized with bidentate Schiff base ligands 4-(2-hydroxy-3 methoxybenzylideneamino) -N-(4-methylpyrimidin-2-yl) benzenesulfonamide (L-1) and 4-(2-hydroxybenzylideneamino)-N-(4methylpyrimidin -2-yl) benzenesulfonamide (L-2). These complexes were characterized by elemental analysis, IR, UV, PXRD. and mass spectrometry techniques. The surface morphology was characterized by SEM analysis. The ligands act as bidentate and can coordinate with metal ions through nitrogen of the azomethine and oxygen of the phenolic groups present in Schiff bases. The square planer geometry was proposed around copper atom whereas cobalt atom shows octahedral geometry. The in vitro antibacterial activities of all complexes were tested against selected gram positive and gram-negative bacteria like Escherichia coli and Staphylococcus aureus using the disc diffusion method. The spectroscopic study provides insights about the chelation and coordination mode of two different ligands with copper and cobalt metals.