Abstract
The complex Di(p-bromobenzyl) (dibromo) (1, 10-phenanthroline) tin (IV) complex (4BRBR) were synthesized and experimentally proved at FT-IR, FT-Raman, 1HNMR, 13CNMR, 119SnNMR and XRD. DFT method used for comparison of theoretical and experimental method, theoretical method optimized to use for B3LYP/LanL2DZ basic set level. The complete vibrational spectral investigation was designed from VEDA program package. Quantum chemical calculated with help of Multiwfn software package. X-ray study confirmed the complex and crystallization by monoclinic space group with P21/c, hydrogen bonding formed through bromine atom such as C---H---Br (Sn-Br---H-Phen), and weak interaction observed at C---H---Br. The crystal of the complex 4BRBR shows tin atom is in regular octahedral geometry. Finally anticancer activity also studied in this complex in various cell lines like PC3 (Human prostate cancer cell), MCF7 (Breast cancer cell), U937 (Blood cancer cell) and U87 Brain cancer cell). The anticancer activity results clearly indicate the MCF7 cell line (Breast cancer cell) has higher anticancer activity compared to standard drug cisplatin and other cell lines which is 7.8 µg/ml concentrations.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
