Abstract
Three racemic esters based on the 1,5-diarylpyrrole structure, which proved to be highly selective COX-2 inhibitors endowed with an appreciable anti-inflammatory activity in some animal models, were subjected to chiral resolution. Their absolute configurations were assigned by comparison of the CD spectrum measured on-line with a HPLC–CD detector, with that calculated by means of a TDDFT method.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
