Synthesis, reactivity and X-ray molecular structure of the activated ester complex [( η5-C 5H 4COONS)Co(CO) 2](NS ; N-succinimidyl)

Abstract

The title compound [( η 5-C 5H 4COONS)Co(CO) 2] ( 2) was prepared in high yield (91%) by treatment of the organometallic carboxylic acid [( η 5-C 5H 4COOH)Co(CO) 2] ( 1) with N-hydroxysuccinimide in the presence of dicyclohexylcarbodiimide. The activated ester complex 2 was identified by spectroscopic methods, in addition its X-ray structure was determined. Compound 2 crystallizes in the triclinic space group P1 with a = 6.1880(8), b = 9.722(1), c = 10.869(1) Å, α = 83.37(1), β = 83.91(1) and γ = 86.30(1)°, V = 645(1) Å3 and Z = 2. The stability of the above species 2 and its reactivity as labelling agent for amines and amino-esters are investigated and discussed.