Abstract
AbstractBy starting with 3′‐keto‐5′‐O‐protected thymidine, 3′‐O‐amino‐5′‐t‐butyl‐diphenylsilyl thymidine (9) was prepared and coupled with 3′‐O‐t‐butyl‐diphenylsilyl‐5′‐formyl thymidine to form a nucleoside dimer (11) containing oxime linkage. The back bone of this dimer, then, under went reduction followed by acetylation to give an (N‐acetyl)imino linkage, and a novel dinucleotide (13) was obtained.
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