Abstract
A general and efficient protocol for the synthesis of thioesters-functionalized 2H-benzopyrans has been developed through a palladium-catalyzed one-pot cyclization/thiocarbonylation reaction of propargyl ethers with sulfonyl chlorides as promising and easily accessible sulfur sources. The reaction showed good compatibility towards versatile functional groups, both aryl and alkylsulfonyl chlorides were well tolerated. Without any external reductant, using Mo(CO)6 as a convenient CO source, a wide range of 2H-benzopyrans bearing thioester as an attractive functional group were obtained in moderate to good yields.
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