Abstract

1. Total syntheses were carried out for (±)-D-Homo-18-nor-9(11)-androstene-3,17a-diol diacetic ester (VIII) and various derivatives of (±)-D-homo-18-norandrostene containing oxygen at C15: (IV), (V), (VI), (VII), (XV), (XVa). 2. With the aid of models an examination was made of the spatial orientation in the condensation of the bicyclic trans dienone (I) with p-benzoquinone, and conclusions were drawn concerning the configurations of the adducts (II) and (IIa). 3. The reduction and hydrogenation of the triones (II)-(IV) were studied.

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