Abstract
Abstract The synthesis of some enantiomerically pure carbocyclic 2′,3′-dideoxy-3′-C-hydroxymethyl derivatives of adenine, inosine and guanine is described. The Mitsunobu reaction was used in the coupling procedure giving exclusively N9-coupling. The nucleosides were tested for inhibition of HIV multiplication in vitro and were found to be inactive in the assay.
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