Abstract
α-Oxy/thio substituted-β-keto esters were synthesized through an efficient cross-Claisen condensation of aryl oxy/thio acetic acid ethyl esters with acid chlorides, then it is converted in situ into 4-oxy/thio substituted-1 H-pyrazol-5(4 H)-ones by the addition of hydrazine or hydrazine derivatives and screened for their antibacterial, antifungal activities.
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