Abstract

SYNTHESIS of some new Aryl-azopyridone analogues was synthesized through coupling of diverse Diazonium salts with 1-ethyl-4-methyl-2,6-dioxopiperidine-3-carbonitrile. The proper structures for all incorporated derivatives were demonstrated to be confirmed via various physical and spectral analyses performed. The synthesized analogues were probed as cytotoxic agents toward four dissimilar cell lines, in which the results displayed persuasive activities relative to the results of antibiotic standards. In addition, the antioxidant activity of the synthesized analogues was evaluated using ABTS•+ method.

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