Abstract
In this paper, a series of 13-aryl-6,13-dihydro-3H-quino(4,3-b)pyrrolo(3,2-f)quinolin-12(11H)-one derivatives was synthesized in EtOH under catalyst-free conditions using aromatic aldehydes, 5-aminoindole and 4-hydroxyquinolin-2(1H)- one as reactants. The structure of 4b was confirmed by X-ray diffraction analysis. This procedure has the advantages of sim- plicity and easy operation. An efficient method for the synthesis of fused pentacyclic heterocycles containing biquinolines moieties is provided. Keywords quinopyrroloquinoline; 5-aminoindole; catalyst-free; synthesis
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