Synthesis of quinazolinone derivatives via a visible-light photocatalyzed denitrogenation rearrangement process

Abstract

The photoredox chemistry has been proposed to rely on the ability of photoexcited catalysts to engage in single-electron-transfer with organic molecules, and energy transfer, the fundamental decay pathway of photoexcited states, is also a catalytic mode for the photoredox chemistry. Although the triplet–triplet energy transfer process is considered to be a powerful activation mechanism in organic photochemistry, it has not been widely applied in organic transformations. Here, we demonstrate a novel visible light photocatalysis by such an activation method: the energy transfer from photoexcited *Ir(ppy)3 produces excited-state 1,2,3-benzotriazinones for the synthesis of quinazolinone derivatives. This method offers a mild and operationally simple access to diverse quinazolinone derivatives with a broad substrate scope.