Abstract
Quaternary ammonium salts containing dithiocarbamate moiety were synthesized and evaluated for their antifungal activities against Helminthosporium oryzae. All the synthesized compounds showed moderate to promising fungitoxicity against the test. Some of the synthesized compounds inflicted antifungal activity greater than the standard fungicide. QUATS containing dithiocarbamate moiety were synthesized and evaluated for their antifungal activities against Helminthosporium oryzae. The synthesized compounds showed promising antifungal potential against the phytopathogenic test fungi. Hexyl-1-(2-hydroxy-3-(piperidine-1-carbonothioylthio)propyl)piperidinium bromide (5b) has shown ED50 value of 302\(\upmu\)g/ml, which was greater than the standard fungicide, Indofil M45(ED50 35\(\upmu\)g/ml) having only thiocarbamate moiety.
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