Synthesis of polyoxymethylene derivatives of 1-oxytriaz-1-ene 2-oxides as the novel promising donors of nitric oxide in the living organisms

Abstract

Novel both symmetric and asymmetric polyoxymethylene derivatives of bis(oxytriazene N-oxides) were synthesized by the nucleophilic substitution of bis(chloromethyl) ether with salts of oxytriazene N-oxides, their pharmacological properties were preliminary evaluated.