Synthesis of Phthaleins with a Chiral Carbon Atom

Abstract

Phthaleins (PE) with a chiral carbon atom - phenyl phenol PE, phenyl resorcinol PE, phenyl catechol PE, phenyl quinol PE, phenyl pyrogallol PE, phenyl phloroglucinol PE and phenyl orcinol PE have been obtained by condensing 2-benzoyl benzoic acid with appropriate phenols. The structure of phenyl resorcinol phthalein, which was found to exist in two isomeric forms, based on chemical reactions and spectral data has been discussed. The Amax values for most of the dyes were found higher than their analogous phthaleins.