Synthesis of PdII Triazolylidene Complexes via an Unusual Csp2‐Csp2 Decoupling Reaction: Applications in α‐Arylation of Amide and Suzuki‐Miyaura Coupling Reactions

Abstract

AbstractMononuclear PdII complexes bearing mixed MIC/Py/PPh3 donor set ligands are presented starting from a bis‐triazolium salt featuring 4,4’‐substitution pattern of central biphenyl ring. The mononuclear PEPPSI (pyridine enhanced precatalyst preparation, stabilization and initiation) type complexes bearing triazolylidene donor ligand have been synthesized via an unusual Csp2‐Csp2 decoupling reaction. The complexes have been characterized by 1H, 13C{1H} NMR spectroscopy and mass spectrometry. Two of the complexes have also been structurally characterized by single crystal XRD. All the complexes appeared as active precatalysts in α‐arylation of amide and Suzuki‐Miyaura coupling reactions. Catalytic outcomes clearly indicate the superior activities of the PdII complexes with mixed MIC/PPh3 donor set ligands compared to the corresponding PEPPSI type complexes in α‐arylation of oxindole.