Synthesis of Oxide Iron Nanoparticles Using Laser Ablation for Possible Hyperthermia Applications.

María J Rivera-Chaverra,Rogelio Ospina,Alexandre Mello,Carlos D Acosta-Medina,Elisabeth Restrepo-Parra

doi:10.3390/nano10112099

Abstract

In this work, iron oxide nanoparticles produced using the laser ablation technique were studied in order to determine the characteristics of these nanoparticles as a function of the laser energy for the possible application in magnetic hyperthermia. Nanoparticles were obtained by varying the power of the laser considering values of 90, 173, 279 and 370 mJ. The morphology of these nanoparticles was determined using the dynamic light scattering (DLS) and scattering transmission electron microscopy (STEM) techniques, confirming that the size of the particles was in the order of nanometers. A great influence of the laser power on the particle size was also observed, caused by the competition between the energy and the temperature. The composition was determined by X-ray diffraction and Raman spectroscopy, showing the presence of magnetite, maghemite and hematite. The hyperthermia measurements showed that the temperature rise of the iron oxide nanoparticles was not greatly influenced by the energy change, the heating capacity of magnetic NPs is quantified by the specific absorption rate (SAR), that tends to decrease with increasing energy, which indicates a dependence of these values on the nanoparticles concentration.

Highlights

Many researchers have studied the synthesis of nanoparticles for several applications
The importance of these nanostructures lies in the characteristics that the nanoparticles possess, different from the characteristics of the bulk materials of the same composition, which is mainly due to the size effects
Magnetic nanoparticles can be used in different fields of application such as nanotechnology, bioenvironmental, physical medicine, and engineering, among others [2]

Summary

Introduction

Many researchers have studied the synthesis of nanoparticles for several applications. The magnetic and electronic properties are strongly influenced by surface phenomena as the size is reduced [2,3] For this reason, magnetic nanoparticles exhibit unique physicochemical properties, such as superparamagnetism, high surface/volume ratio, strong magnetic response, and low toxicity [4], depending on their size and shape. Magnetic nanoparticles exhibit unique physicochemical properties, such as superparamagnetism, high surface/volume ratio, strong magnetic response, and low toxicity [4], depending on their size and shape This special behavior makes them suitable candidates for a wide variety of applications in areas such as magnetic recording [5], and biomedicine [6,7] among others. These types of nanostructures have been used to support diagnosis in magnetic resonance imaging, administration of drugs and their targeted delivery, in addition to environmental remediation, plant growth, catalysis, etc. [8,9]

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