Abstract
Herein we report the synthesis of biologically relevant oxazino[4,3-a]indoles by an environmentally friendly Michael addition-cyclization cascade using potassium hydroxide in dichloromethane employing variously substituted vinyl selenones and (1H-indol-2yl)methanols.The addition of 18-crown-6, as a complexing agent, is crucial to achieve high chemo- and regio-selectivity.
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