Abstract
The regioselective synthesis of an amphiphilic chitosan derivative, O, O′-dipalmitoyl chitosan (DPCT) was achieved by the selective protection of amino groups in MeSO 3H. The amphiphilic behavior and miscibility with cholesterol of DPCT were studied through Langmuir–Blodgett (LB) technique. The condensed monolayer formed at water–air interface had a collapse pressure of 40 mN m −1 and could be transferred onto various substrates by Langmuir–Blodgett technique. Furthermore, this amphiphilic chitosan with free amino groups was cross-linked with glutaraldehyde. The adsorption behavior of the cross-linked amphiphilic chitosan to cholesterol was also studied. The results showed that this cross-linked amphiphilic chitosan could effectively adsorb cholesterol both in polar and in non-polar solvents.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.