Abstract
The main aim of the present work was to synthesis a series of novel thiazolidin-4-one derivatives of 7-hydroxy- 4-methyl coumarinyl acetic hydrazide. The synthesis majorly involves six steps, where the synthesis of coumarin molecules with thiazolidin-4-one was reported with its activity study. Here ten novel derivatives of compounds were synthesized and evaluated for their antioxidant and in vitro cytotoxicity against DLA cells. Some of the compounds showed promising activity for the antioxidant and in vitro cytotoxic activity against DLA and thus these compounds represent a new class of promising lead compounds.
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