Synthesis of novel organotin(IV) complex for multiple applications: as biologically potent and single molecular precursor

Abstract

This work reports a facile solution-based synthesis of novel single molecular precursor (SMP), triphenylstannyl 4-((4-bromophenyl) amino)-4-oxobut-2-enoate complex (2). The as-prepared SMP was characterized by single crystal X-rays diffraction, elemental analysis, 1H NMR, 13C NMR and Mass spectrometry. The thermal properties of as-prepared SMP were assessed by thermogravimetric analysis and differential calorimetry. The as-prepared complex showed excellent DNA binding property in vivo experiments. The as-prepared complex (2) also revealed good antileishmanial and anticancer properties. Lastly, high-quality transparent SnO2 thin films were obtained by aerosol-assisted chemical vapors deposition on common window glass. The morphological and structural studies of as-deposited thin films were performed by XRD and FE-SEM.