Synthesis of novel macrolides-linked chalcone derivatives and recognition ability toward Cu2+

Abstract

A series of novel macrolides-linked chalcone derivatives 2a–c and 3a–d were synthesized from compounds 1a–d with 1,2-benzenedicarbonyl chloride. Their structures were confirmed by IR, 1H NMR, and high resolution mass spectrometry. The crystal structure of compound 2a was characterized by single crystal X-ray diffractometry. The ions recognition experiments were carried out and showed that the title compound 3d displayed selective recognition toward Cu2+.