Abstract
A number of novel oxa-bridged and methylene oxa-bridged bicyclic isoxazolidines have been synthesized using intramolecular nitrone cycloaddition. The reductive cleavage of N-O bonds of the isoxazolidines to provide novel medium-ring heterocycles oxazocines and oxazonines is also described. Keywords: Isoxazolidines, oxazocines, oxazonines, amino alcohols, medium-ring heterocycles, oxa-bridged, methylene, nitrone, cycloaddition, benzoxazocine
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