Synthesis of novel functionalized hydroxyiminoimines by direct nitrosation of β-thio-β-amino-α,β- unsaturated ketones and their further transformations: new general syntheses for imidazole, quinoxaline, and thiazole derivatives

Abstract

New general methods for the synthesis of imidazole (3), (10), quinoxaline (6), and thiazole (9) derivatives have been developed from the corresponding novel functionalized 1,2-hydroxyiminoimines (2), (5), and (8) obtained by direct nitrosation of β-thio-β-amino-α,β-unsaturated ketones with nitrosyl chloride.