Abstract
We have developed an efficient and environ- mentally benign one-pot procedure for synthesis of novel N-alkyl-2-aryl-5-phenylimidazo(1,2-c)quinazolin-3-amine derivatives by use of the Groebke-Blackburn-Bienayme ´ multicomponent reaction. The title compounds were syn- thesized in good yields from 2-phenylquinazolin-4-amine, aromatic aldehydes, and isocyanides in the presence of ammonium chloride under solvent-free conditions.
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