Abstract

2,4-disubstituted quinoline derivative (2-(2-nitrophenyl)quinolin-4-yl)methanol 1 was synthesized by using multicomponent reaction of aniline, 2-nitro benzaldehyde and propargyl alcohol in the presence of copper bromide. From compound 1, we prepared novel series of 2,4-disubstituted quinoline analogs. The synthesized compounds (1-6) were characterized by NMR and mass spectra.

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