Abstract

New series of thiourea and thiazolidinone derivatives containing a 1,8-dioxo octahydroacridinyl moiety have been synthesized through the reaction of 1-(4-Amino-phenyl)-3-methyl-thiourea with various aromatic aldehydes and dimedone. All the synthesized compounds were tested against several microbial pathogens Staphylococcus aureus, Micrococcus luteus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Candida albicans.

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