Abstract
Four new cyclobutane-containing building blocks were synthesized on a multigram scale starting from 3-methylene-1-(trifluoromethyl)cyclobutane-1-carbonitrile and 3-methylene-1-(trifluoromethyl)cyclobutane-1-carboxylic acid. The synthesized compounds contain trifluoromethyl group near the functional one (carboxylic or amino group) and are promising for further application in drug discovery
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