Synthesis of NiO/CNTs Nanocomposite by Direct Chemical Precipitation Method for Preparation of Voltammetric Sensor in Acetaminophen Analysis

Abstract

Although acetaminophen is a widely used analgesics and antipyretic drug, its overdose leads to many complications. Therefore, determining the correct dose of produced or imported drugs in clinical laboratories or a standard laboratory is essential. Different analytical methods, for example chromatography, spectroscopy and electrochemistry, can be utilized to determine the correct dose of acetaminophen. However, it is believed that electrochemical methods are more efficient due to their fast response and low cost. In this study, we synthesized NiO/CNTs nanocomposite by a direct chemical precipitation method for acetaminophen analysis using a voltammetric sensor. A chemical precipitation method was used for synthesis of NiO/CNTs nanocomposite in the nanoscale. The synthesis of nanopowder was investigated using scanning electron microscopy (SEM) and X-ray powder diffraction. The obtained result confirms the synthesis of nanocomposite with chemical precipitation method with ~35.5 nm diameter for NiO nanoparticle, as established by the Scherrer equation. The results show that the synthesized nanocomposite can modify a carbon paste electrode as a sensor for the analysis of acetaminophen.