Abstract
An efficient five-step procedure for synthesis of unsymmetrical imidazolinium salts with mesityl and nitrophenyl substituents was elaborated. The starting nitroaniline was acylated with chloroacetyl chloride followed by Finkelstein displacement by iodide and coupling with mesitylamine. The key step was reduction of the amide carbonyl group with BH3·S(CH3)2. Finally, an imidazoline ring was constructed by reaction with trimethyl orthoformate. A different approach was attempted for 2,6-dinitroaniline, but final cyclization failed in this case.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.