Abstract
The synthesis of new polyamides from two natural compounds L-malic acid and L-lysine was carried out via the active ester polycondensation method (pentafluorophenyl ester). The hydroxyl and carboxylic side groups were orthogonally protected as tert-butyl ether and benzyl ester, respectively. High molecular masses (reaching 25 000 g/mol) were obtained at 60°C in tetrahydrofuran for fully protected polyamide. This polymer was soluble in chloroform. Total regeneration of hydroxyl groups was carried out in trifluoroacetic acid. Regeneration of the carboxylic group by hydrogenolysis led to a polyamide, soluble in Tris buffer solution (pH = 7.4). The polyamides bearing free hydroxyl and carboxyl groups were water-soluble.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.