Abstract
The synthesis of new morphinan opioids by the addition of photochemically generated carbon‐centered radicals to substrates containing an enone in the morphinan C‐ring, is described. Using tetrabutylammonium decatungstate (TBADT) as a hydrogen atom transfer photocatalyst, diverse radical donors can be used to prepare a variety of C8‐functionalized morphinan opioids. This work demonstrates the late‐stage modification of complex, highly functionalized substrates.
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