Abstract
AbstractA short and easy method for the preparation of the 2‐azatricyclo[3.3.0.03,6]octane skeleton is described. The key step consists of an intramolecular ring closure of an endo‐oriented amino group and an exo‐oriented bromine atom. The amines were prepared through reduction of a suitable bicyclic imine. Nucleophilic addition of phosphite to the imines gave the corresponding aminophosphonates, which could be ring‐closed to the tricyclic aminophosphonates through an analogous pathway. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
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