Synthesis of New Chiral Monosulfonamides Prepared from (11R,12R)-11,12-Diamino-9,10-dihydro-9,10-ethanoanthracene and their Use as Ligands for Asymmetric Catalysis

Abstract

New chiral monosulfonamides …6-16 containing (11R,12R)-diamino-9,10-dihydro-9,10-ethanoanthracene as carbon skeleton were prepared. Compounds 6-12, 15 and 16 were used as optically active ligands in the enantioselective ethylation of benzaldehyde. Moreover, the monosulfonamides 6-10 were tested in the asymmetric transfer hydrogenation (ATH) of acetophenone with Rh(Cp*)L* complex.