Abstract
A new series of bis- and tetra-acridines has been prepared from 4-(bromo-methyl)acridine; some of them exhibited encouraging in vitro cytotoxic activities against murine cell lines.
Highlights
Acridine derivatives are well known therapeutic agents whose mutagenic properties depend on their ability to interact with nucleic acids
We propose an easy way to prepare a new class of polyacridinic derivatives using 4-(bromomethyl)acridines
Most of them display some biological activity and we are expanding the scope of this approach to the synthesis of other polyacridines
Summary
Acridine derivatives are well known therapeutic agents whose mutagenic properties depend on their ability to interact with nucleic acids.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
