Abstract

Phthalic thioanhydride reacted with ise-butylamine, benzylamine, cyclohexylamine, b-aminobenzoic acid, P-aminobenzenesulfoAamide, o-aminobenzamide, and o-phenylenediamine in ethanol at 80C, with the evolution of hydrogen suifide, to afford N-substituted phthalimides in good yields.Phthaloylation of glycine, B-alanine, and o-aminobenzoiacid was also achieved under basic reactions conditions. A probable reaction route is disussed.

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