Abstract
Baylis–Hillman acetates were synthesized from substituted 2-chloronicotinaldehydes and were conveniently transformed into multisubstituted quinolines and cyclopenta[ g]quinolines on reaction with nitroethane or ethyl cyanoacetate via a successive S N2′–S NAr elimination strategy. Thus, synthesized quinolines were evaluated for antimicrobial activity and found having substantial antibacterial and antifungal activity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have